Description

2,3-Dimethoxystrychnidin-10-One (S)-1-(tert-Butoxycarbonyl)Pyrrolidine-2-Carboxylic Acid Ethyl Ester Monohydrate is a high-purity, complex organic intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key chiral building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in complex organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct molecules with specific three-dimensional configurations.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring high enantiomeric purity.
• Academic & Industrial R&D: A key reagent for synthetic organic chemists in both academic research and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	2,3-Dimethoxystrychnidin-10-One (S)-1-(tert-Butoxycarbonyl)Pyrrolidine-2-Carboxylic Acid Ethyl Ester Monohydrate
CAS No.	908012-07-7
Molecular Formula	C28H38N2O8 • H2O
Molecular Weight	548.62 g/mol (Monohydrate)
Synonyms	(S)-1-Boc-Pyrrolidine-2-carboxylic Acid Ethyl Ester Derivative; Ethyl (S)-1-[(tert-Butoxy)carbonyl]pyrrolidine-2-carboxylate Strychnine Derivative; 2,3-Dimethoxystrychnidin-10-one Boc-Pro-OEt Monohydrate; Strychnine-10-one, 2,3-dimethoxy-, (S)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate ethyl ester monohydrate; Complex Strychnine Alkaloid Intermediate; Chiral Pyrrolidine Ester Intermediate; API Intermediate 908012-07-7
EINECS	Contact for details

Quality Control

Our 2,3-Dimethoxystrychnidin-10-One (S)-1-(tert-Butoxycarbonyl)Pyrrolidine-2-Carboxylic Acid Ethyl Ester Monohydrate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and related substances are provided and available upon request, supporting compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	3.0% - 5.0% (Theoretical for monohydrate ~3.28%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.