Description

4-[6-(Trifluoromethyl)Imidazo-[1,2-A]Pyridin-2-Yl]Benzonitrile is a high-value, heterocyclic organic compound featuring a fused imidazopyridine core functionalized with a trifluoromethyl group and a benzonitrile moiety. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients. The compound's structure is engineered to modulate biological activity and physicochemical properties in target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology, CNS disorders, and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Used in the research and development of new-generation herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Material Science: Investigated as a building block for organic electronic materials, such as OLEDs or semiconductors, where the trifluoromethyl and nitrile groups can influence electron affinity and stability.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical pathway analysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production for clinical trials.

Basic Information

Product Name	4-[6-(Trifluoromethyl)Imidazo-[1,2-A]Pyridin-2-Yl]Benzonitrile
CAS No.	907960-23-0
Molecular Formula	C15H8F3N3
Molecular Weight	287.24 g/mol
Synonyms	4-(6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)benzonitrile; 2-(4-Cyanophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine; 907960-23-0; 4-(6-Trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzonitrile; 6-(Trifluoromethyl)-2-(4-cyanophenyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-[4-(cyanophenyl)]-6-(trifluoromethyl)-; 4-(6-Trifluoromethyl-imidazo[1,2-a]pyridin-2-yl)-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[6-(Trifluoromethyl)Imidazo-[1,2-A]Pyridin-2-Yl]Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.