Description

tert-Butyl (3S,4R)-4-Amino-3-Fluoropiperidine-1-Carboxylate is a high-purity, stereochemically defined fluorinated piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a protected amino-fluoro-piperidine scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, particularly in the development of active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Protease Inhibitor Development: Used in constructing pharmacophores for inhibitors targeting various enzymes.
• Peptidomimetics: Incorporation into peptide analogs to enhance metabolic stability and binding affinity.
• Agrochemical Research: Serves as a building block for developing advanced, fluorinated active ingredients with improved properties.
• Ligand Synthesis: For creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological pathways and protein function.

Basic Information

Product Name	tert-Butyl (3S,4R)-4-Amino-3-Fluoropiperidine-1-Carboxylate
CAS No.	907544-20-1
Molecular Formula	C10H19FN2O2
Molecular Weight	218.27 g/mol
Synonyms	1-Boc-4-amino-3-fluoropiperidine (3S,4R)-isomer; (3S,4R)-1-(tert-Butoxycarbonyl)-4-amino-3-fluoropiperidine; tert-Butyl (3S,4R)-4-amino-3-fluoropiperidine-1-carboxylate; 4-Amino-3-fluoro-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester, (3S,4R)-; (3S,4R)-4-Amino-3-fluoro-N-Boc-piperidine; N-Boc-(3S,4R)-4-amino-3-fluoropiperidine; 907544-20-1; Boc-Amino-fluoro-piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S,4R)-4-Amino-3-Fluoropiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.