Description

(1R,2S)-2-(4-Bromo-Phenyl)-Cyclopropyl-Carbamic Acid tert-Butyl Ester is a high-purity chiral building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which are critical for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Key chiral intermediate in the research and development of novel pharmaceutical candidates, particularly for central nervous system (CNS) and antiviral targets.
• Building block for the synthesis of advanced agrochemicals, where its stereochemistry can influence biological activity and environmental selectivity.
• Precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Starting material for the preparation of more complex, functionalized cyclopropane derivatives used in asymmetric catalysis and material science.
• Reference standard for analytical method development and quality control in the production of stereochemically defined APIs.

Basic Information

Product Name	(1R,2S)-2-(4-Bromo-Phenyl)-Cyclopropyl-Carbamic Acid tert-Butyl Ester
CAS No.	907196-12-7
Molecular Formula	C14H18BrNO2
Molecular Weight	312.20 g/mol
Synonyms	tert-Butyl N-[(1R,2S)-2-(4-bromophenyl)cyclopropyl]carbamate; (1R,2S)-rel-2-(4-Bromophenyl)cyclopropanecarboxylic acid tert-butylamide; BOC-(1R,2S)-2-(4-Bromophenyl)cyclopropylamine; N-Boc-(1R,2S)-2-(4-bromophenyl)cyclopropanamine; (1R,2S)-2-(4-Bromophenyl)cyclopropylcarbamic acid 1,1-dimethylethyl ester; (1R,2S)-2-(p-Bromophenyl)cyclopropylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of (1R,2S)-2-(4-Bromo-Phenyl)-Cyclopropyl-Carbamic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical R&D and can provide material compliant with cGMP guidelines for non-clinical development stages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.