Description

tert-Butyl n-(5-Hydroxypyridin-3-Yl)Carbamate is a high-purity, protected pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The carbamate and hydroxypyridine functionalities make it valuable for designing peptide analogs and enzyme inhibitors.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring a protected aminopyridine moiety.

Basic Information

Product Name	tert-Butyl n-(5-Hydroxypyridin-3-Yl)Carbamate
CAS No.	906745-11-7
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	tert-Butyl (5-Hydroxy-3-pyridinyl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-pyridinol; 5-Hydroxy-3-pyridinylcarbamic Acid tert-Butyl Ester; N-Boc-5-Hydroxy-3-aminopyridine; Boc-5-Hydroxy-3-aminopyridine; tert-Butyl N-(5-Hydroxypyridin-3-yl)carbamate; 3-Amino-5-hydroxypyridine N-Boc protected; 5-Hydroxy-3-pyridinamine, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(5-Hydroxypyridin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.