Description

Methyl 4-Acetoxy-6-Acetoxymethyl-5-Benzyloxynicotinate is a high-purity, multi-functional nicotinate derivative serving as a critical advanced intermediate in complex organic synthesis. Its value lies in its versatile reactivity, offering multiple protected functional groups that enable precise, multi-step chemical transformations. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing complex pyridine or nicotinic acid-based structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific nicotinate motifs are required for biological activity.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry, medicinal chemistry, and method development.
• Process Chemistry: Employed in scale-up and optimization studies for the production of fine chemicals and active ingredients, leveraging its protected functional groups for selective reactions.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Item	Details
Product Name	Methyl 4-Acetoxy-6-Acetoxymethyl-5-Benzyloxynicotinate
CAS No.	906657-90-7
Molecular Formula	C19H19NO7
Molecular Weight	373.36 g/mol
Synonyms	Methyl 5-(benzyloxy)-4,6-bis(acetoxymethyl)nicotinate; 5-Benzyloxy-4,6-bis(acetoxymethyl)nicotinic acid methyl ester; Methyl 5-benzyloxy-4,6-bis(acetoxymethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(phenylmethoxy)-4,6-bis(acetyloxy)methyl-, methyl ester; Methyl 4,6-bis(acetoxymethyl)-5-benzyloxynicotinate; 906657-90-7; Nicotinic acid derivative CAS 906657-90-7
EINECS	Contact for details

Quality Control

Our Methyl 4-Acetoxy-6-Acetoxymethyl-5-Benzyloxynicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets exacting standards for research and process use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.