Description

2-(4-Isocyanatophenyl)-5-(Trifluoromethyl)Pyridine is a specialized aromatic isocyanate building block, distinguished by the presence of a pyridine ring and a trifluoromethyl group. This unique molecular architecture makes it a high-value intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where electronic properties and stability are critical. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced polymer industries for creating novel compounds with tailored functionalities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research where the pyridine and trifluoromethyl motifs are prevalent.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require specific bioactivity and environmental stability.
• Advanced Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polyurethanes, polyimides, and other specialty polymers with enhanced thermal and chemical resistance.
• Liquid Crystal & OLED Materials: Incorporated into the molecular design of electronic materials for displays and lighting due to its ability to influence molecular alignment and electronic properties.
• Organic Synthesis & Chemical Research: A versatile reagent for constructing complex heterocyclic systems and introducing the isocyanate functional group in multi-step synthetic routes.

Basic Information

Product Name	2-(4-Isocyanatophenyl)-5-(Trifluoromethyl)Pyridine
CAS No.	906352-73-6
Molecular Formula	C13H7F3N2O
Molecular Weight	264.21 g/mol
Synonyms	5-(Trifluoromethyl)-2-(4-isocyanatophenyl)pyridine; 4-(5-(Trifluoromethyl)pyridin-2-yl)phenyl isocyanate; 2-(4-Isocyanatophenyl)-5-(trifluoromethyl)pyridine; 4-(5-Trifluoromethyl-2-pyridinyl)phenyl isocyanate; [4-(5-Trifluoromethylpyridin-2-yl)phenyl] isocyanate
EINECS	Contact for details

Quality Control

Our production of 2-(4-Isocyanatophenyl)-5-(Trifluoromethyl)Pyridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.