Description

Ethyl 3-(2,6-Dichloro-5-Fluoropyridin-3-Yl)-3-Oxopropanoate is a high-value fluorinated pyridine derivative and a key β-ketoester intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals, offering a versatile building block for constructing heterocyclic frameworks. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require fluorinated pyridine motifs for enhanced efficacy and selectivity.
• Chemical Research & Development: Serves as a versatile precursor for developing new heterocyclic compounds in academic and industrial R&D laboratories.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of final APIs, especially in segments requiring fluorinated and chlorinated pyridine structures.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	Ethyl 3-(2,6-Dichloro-5-Fluoropyridin-3-Yl)-3-Oxopropanoate
CAS No.	905808-04-0
Molecular Formula	C10H8Cl2FNO3
Molecular Weight	280.08 g/mol
Synonyms	Ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropanoate; 3-Oxopropanoic acid, 3-(2,6-dichloro-5-fluoro-3-pyridinyl)-, ethyl ester; Ethyl (2,6-dichloro-5-fluoro-3-pyridinyl)oxoacetate; 2,6-Dichloro-5-fluoro-3-pyridineacetic acid, β-oxo-, ethyl ester; Ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropionate; 905808-04-0; 3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3-oxopropanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2,6-Dichloro-5-Fluoropyridin-3-Yl)-3-Oxopropanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.