Description

Methyl 3-Bromo-5-Iodo-4-Methylbenzoate is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical research and material science. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of both bromo and iodo substituents, allowing for sequential, selective functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Methyl 3-Bromo-5-Iodo-4-Methylbenzoate
CAS No.	905712-38-1
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	3-Bromo-5-iodo-4-methylbenzoic acid methyl ester; Methyl 3-bromo-5-iodo-p-toluate; Benzoic acid, 3-bromo-5-iodo-4-methyl-, methyl ester; 4-Methyl-3,5-dibromobenzoic acid methyl ester (incorrect but common search variant); 905712-38-1; Methyl 3,5-dihalo-4-methylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Iodo-4-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.