Description

(S)-1-(5-Fluoropyridin-2-yl)ethanamine is a chiral amine building block featuring a fluorinated pyridine core. This compound is of significant commercial interest due to its role as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis for fine chemical synthesis.
• Chemical Research: A valuable building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Material Science: Potential use in the synthesis of specialty polymers and advanced materials requiring fluorinated aromatic components.

Basic Information

Product Name	(S)-1-(5-Fluoropyridin-2-yl)ethanamine
CAS No.	905587-15-7
Molecular Formula	C7H9FN2
Molecular Weight	140.16 g/mol
Synonyms	(S)-1-(5-Fluoropyridin-2-yl)ethan-1-amine; (S)-1-(5-Fluoro-2-pyridinyl)ethylamine; (S)-α-Methyl-5-fluoropyridine-2-methanamine; (S)-5-Fluoro-2-(1-aminoethyl)pyridine; (S)-2-(1-Aminoethyl)-5-fluoropyridine; (S)-5-Fluoro-Py-2-EA; (S)-FPEA
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Fluoropyridin-2-yl)ethanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.