Description

3-Chloro-5-Methoxyisonicotinaldehyde is a versatile pyridine-based aldehyde building block, identified by CAS number 905563-83-9. This compound is of significant value in advanced organic synthesis, where its reactive aldehyde group and halogen-substituted heterocyclic core enable the construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its functionalized pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functional organic materials, such as liquid crystals or organic semiconductors, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Chloro-5-Methoxyisonicotinaldehyde
CAS No.	905563-83-9
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	5-Methoxy-3-chloroisonicotinaldehyde; 3-Chloro-5-methoxypyridine-4-carbaldehyde; 4-Pyridinecarboxaldehyde, 3-chloro-5-methoxy-; Isonicotinaldehyde, 3-chloro-5-methoxy-; 3-Chloro-5-methoxy-4-formylpyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methoxyisonicotinaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.