Description

2-Chloro-3-Methoxypyridine-4-Carboxaldehyde is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and aldehyde functional groups, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom chemical synthesis services and scale-up processes under cGMP conditions.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-Chloro-3-Methoxypyridine-4-Carboxaldehyde
CAS No.	905563-05-5
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	4-Formyl-2-chloro-3-methoxypyridine; 2-Chloro-3-methoxy-4-pyridinecarboxaldehyde; 2-Chloro-3-methoxypyridine-4-carbaldehyde; 3-Methoxy-2-chloropyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 2-chloro-3-methoxy-; 905563-05-5; 2-Chloro-3-methoxypyridine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methoxypyridine-4-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.