Description

6-(Trifluoromethyl)-1H,2H,3H-Pyrrolo[3,4-C]Pyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused pyrrolopyridine scaffold with a strategically positioned trifluoromethyl group, makes it a critical intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets, where the trifluoromethyl group can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms to improve biological activity and environmental persistence profiles.
• Material Science Research: Employed as a building block for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where fluorinated heterocycles can tune electronic properties.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in transition metal catalysis, facilitating various cross-coupling and asymmetric synthesis reactions.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement within complex systems.

Basic Information

Product Name	6-(Trifluoromethyl)-1H,2H,3H-Pyrrolo[3,4-C]Pyridine
CAS No.	905275-83-4
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	6-(Trifluoromethyl)-1H,2H,3H-pyrrolo[3,4-c]pyridine; 1H,2H,3H-Pyrrolo[3,4-c]pyridine, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine; 6-Trifluoromethyl-1H,2H,3H-pyrrolo[3,4-c]pyridine; 6-Trifluoromethyl-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine; 6-(Trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine; 905275-83-4; 6-Trifluoromethylpyrrolo[3,4-c]pyridine
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-1H,2H,3H-Pyrrolo[3,4-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.