Description

6-Chloro-2,3-Dihydro-1H-Pyrrolo[3,4-C]Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 905273-90-7. This compound is a critical building block in modern medicinal chemistry, valued for its fused pyrrolopyridine scaffold which is integral to developing bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Drug Development: Used in the research and development of kinase inhibitors and other targeted cancer therapies.
• CNS-Active Compound Synthesis: Employed in creating potential candidates for treating neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Item	Detail
Product Name	6-Chloro-2,3-Dihydro-1H-Pyrrolo[3,4-C]Pyridine Hydrochloride
CAS No.	905273-90-7
Molecular Formula	C7H8Cl2N2
Molecular Weight	191.06 g/mol
Synonyms	6-Chloro-1,2,3,5-tetrahydro-4H-pyrrolo[3,4-c]pyridine hydrochloride; 6-Chloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine HCl; 6-Chloro-1,2,3,5-tetrahydro-4H-pyrrolo[3,4-c]pyridin-4-one hydrochloride (tautomer); 905273-90-7; Pyrrolo[3,4-c]pyridine, 6-chloro-2,3-dihydro-1H-, hydrochloride; 6-Chloro-4-oxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,4-c]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,3-Dihydro-1H-Pyrrolo[3,4-C]Pyridine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.