Description

3-(Trifluoromethyl)-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine is a high-value, heterocyclic building block featuring a fused pyrrolopyridine core and a reactive trifluoromethyl group. This compound is critical for medicinal chemistry and agrochemical research, where its unique scaffold enables the synthesis of novel molecules with enhanced biological activity and metabolic stability. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor programs and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	3-(Trifluoromethyl)-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine
CAS No.	905273-66-7
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	3-(Trifluoromethyl)-5H,6H,7H-pyrrolo[3,4-b]pyridine; 6,7-Dihydro-3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridine; 5H-Pyrrolo[3,4-b]pyridine, 6,7-dihydro-3-(trifluoromethyl)-; 3-Trifluoromethyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine; Trifluoromethyl DHP Pyridine; Fused Pyrrolopyridine Trifluoromethyl Derivative
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethyl)-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.