Description

2-(Trifluoromethyl)-6,7-Dihydro-5Hpyrrolo[3,4-B]Pyridine is a high-value, fluorinated heterocyclic building block with the CAS number 905273-59-8. This compound is essential for medicinal chemistry research and development, offering a versatile scaffold for creating novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and CNS-targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged pyrrolopyridine core and trifluoromethyl group.
• Agrochemical Development: Serves as a precursor in the research and synthesis of advanced crop protection agents and herbicides.
• Material Science: Potential use in the development of specialty chemicals and advanced materials, including organic electronic components.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	2-(Trifluoromethyl)-6,7-Dihydro-5Hpyrrolo[3,4-B]Pyridine
CAS No.	905273-59-8
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	2-(Trifluoromethyl)-5,6,7,8-tetrahydropyrrolo[3,4-b]pyridine; 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine, 2-(trifluoromethyl)-; 2-Trifluoromethyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine; 905273-59-8; Pyrrolo[3,4-b]pyridine, 6,7-dihydro-2-(trifluoromethyl)-5H-; 5H-Pyrrolo[3,4-b]pyridine, 6,7-dihydro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-6,7-Dihydro-5Hpyrrolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.