Description

Dimethyl 6-(Trifluoromethyl)Pyridine-2,3-Dicarboxylate is a high-purity, multi-functional pyridine derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of the pyridine core with ester functionalities and a trifluoromethyl group, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to build active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing candidates with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or components for OLEDs and sensors.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of fluorine atoms on chemical reactivity and physical properties in heterocyclic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Dimethyl 6-(Trifluoromethyl)Pyridine-2,3-Dicarboxylate
CAS No.	905273-56-5
Molecular Formula	C10H8F3NO4
Molecular Weight	263.17 g/mol
Synonyms	2,3-Pyridinedicarboxylic acid, 6-(trifluoromethyl)-, dimethyl ester; Dimethyl 6-(trifluoromethyl)pyridine-2,3-dicarboxylate; 6-(Trifluoromethyl)pyridine-2,3-dicarboxylic acid dimethyl ester; Methyl 6-(trifluoromethyl)pyridine-2,3-dicarboxylate; DMTPDC; 905273-56-5
EINECS	Contact for details

Quality Control

Our Dimethyl 6-(Trifluoromethyl)Pyridine-2,3-Dicarboxylate is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent hydrolysis. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.