Description

3-Bromo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine Hydrochloride is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor in the design and synthesis of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies for various disease targets.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery.

Basic Information

Product Name	3-Bromo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine Hydrochloride
CAS No.	905273-36-1
Molecular Formula	C8H8BrClN2
Molecular Weight	247.52 g/mol
Synonyms	3-Bromo-5,6,7,8-tetrahydropyrrolo[3,4-b]pyridine hydrochloride; 3-Bromo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine HCl; 3-Bromo-5,6,7,8-tetrahydro-1H-pyrrolo[3,4-b]pyridine hydrochloride; 905273-36-1; 3-Bromo-5,6,7,8-tetrahydro-pyrrolo[3,4-b]pyridine hydrochloride; 3-Bromotetrahydropyrrolopyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques like HPLC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.