Description

5-Bromo-2,3-Bis-Bromomethyl-Pyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its multi-functional bromomethyl and bromo substituents make it a highly reactive intermediate for constructing complex heterocyclic systems and pharmaceutical scaffolds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific molecular complexity and functionality.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides due to its reactive halogen sites.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Used to create molecular probes and tags for studying biological systems and protein interactions.

Basic Information

Product Name	5-Bromo-2,3-Bis-Bromomethyl-Pyridine
CAS No.	905273-34-9
Molecular Formula	C7H6Br3N
Molecular Weight	343.84 g/mol
Synonyms	2,3-Bis(bromomethyl)-5-bromopyridine; 5-Bromo-2,3-di(bromomethyl)pyridine; Pyridine, 5-bromo-2,3-bis(bromomethyl)-; 5-Bromo-2,3-bis(bromomethyl)pyridine; 2,3-Di(bromomethyl)-5-bromopyridine; 5-Bromo-2,3-dibromomethylpyridine; 905273-34-9 (CAS); 5-Br-2,3-bis-BrCH2-Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Bis-Bromomethyl-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.