Description

2-(2-Pyridin-3-Yl-Pyrrolidin-1-Yl)-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where precise chemical integrity and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and anti-infective agents.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing novel nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of new pharmacophores.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-compliant API production.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-(2-Pyridin-3-Yl-Pyrrolidin-1-Yl)-Nicotinic Acid
CAS No.	904816-83-7
Molecular Formula	C15H15N3O2
Molecular Weight	269.30 g/mol
Synonyms	2-(2-(Pyridin-3-yl)pyrrolidin-1-yl)nicotinic acid; 2-[2-(3-Pyridinyl)-1-pyrrolidinyl]-3-pyridinecarboxylic acid; Nicotinic acid, 2-(2-(3-pyridinyl)-1-pyrrolidinyl)-; 3-Pyridinecarboxylic acid, 2-[2-(3-pyridinyl)-1-pyrrolidinyl]-; 904816-83-7; 2-(2-(3-Pyridyl)pyrrolidin-1-yl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Pyridin-3-Yl-Pyrrolidin-1-Yl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.