Description

2-(2-Phenyl-Pyrrolidin-1-Yl)-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 904816-69-9. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Research & Development: Used in medicinal chemistry for lead optimization and the creation of new chemical entities (NCEs) in academic and industrial labs.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.

Basic Information

Product Name	2-(2-Phenyl-Pyrrolidin-1-Yl)-Nicotinic Acid
CAS No.	904816-69-9
Molecular Formula	C₁₆H₁₆N₂O₂
Molecular Weight	268.31 g/mol
Synonyms	2-(2-Phenylpyrrolidin-1-yl)nicotinic acid; 2-(2-Phenyl-1-pyrrolidinyl)-3-pyridinecarboxylic acid; Nicotinic acid, 2-(2-phenyl-1-pyrrolidinyl)-; 904816-69-9; 2-(2-Phenylpyrrolidin-1-yl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-(2-phenyl-1-pyrrolidinyl)-; 2-(2-Phenyl-1-pyrrolidinyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Phenyl-Pyrrolidin-1-Yl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.