Description

2-(4-tert-Butoxycarbonylamino-Butylamino)-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate featuring a nicotinic acid core with a protected aminoalkyl side chain. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic pathways.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) for high-throughput screening and lead optimization.
• Peptidomimetic Synthesis: Serves as a crucial component for constructing peptide-like molecules with enhanced stability and bioavailability.
• Bioconjugation Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-(4-tert-Butoxycarbonylamino-Butylamino)-Nicotinic Acid
CAS No.	904816-11-1
Molecular Formula	C15H23N3O4
Molecular Weight	309.36 g/mol
Synonyms	2-[(4-{[(tert-Butoxy)carbonyl]amino}butyl)amino]pyridine-3-carboxylic acid; 2-[(4-{[(tert-Butoxy)carbonyl]amino}butyl)amino]nicotinic acid; Boc-4-Aminobutylamino-nicotinic Acid; N-Boc-1,4-diaminobutane nicotinic acid derivative; 3-Pyridinecarboxylic acid, 2-[[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]amino]-; 904816-11-1; tert-Butyl N-[4-[(3-carboxypyridin-2-yl)amino]butyl]carbamate
EINECS	Contact for details

Quality Control

Our 2-(4-tert-Butoxycarbonylamino-Butylamino)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.