Description

n-{2-[(4-Methylphenyl)Sulfonyl]-2-(Pyridin-3-Yl)Ethyl}Thiophene-2-Sulfonamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new drug candidates, particularly in areas requiring complex sulfonamide-based molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for research into kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential biological activity.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical development.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays to study enzyme interactions and signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of pharmaceutical compounds for client projects.

Basic Information

Item	Details
Product Name	n-{2-[(4-Methylphenyl)Sulfonyl]-2-(Pyridin-3-Yl)Ethyl}Thiophene-2-Sulfonamide
CAS No.	904809-04-7
Molecular Formula	C19H20N2O4S3
Molecular Weight	460.57 g/mol
Synonyms	N-[2-[(4-Methylphenyl)sulfonyl]-2-(3-pyridinyl)ethyl]-2-thiophenesulfonamide; 2-Thiophenesulfonamide, N-[2-[(4-methylphenyl)sulfonyl]-2-(3-pyridinyl)ethyl]-; 904809-04-7; n-(2-(p-tolylsulfonyl)-2-(pyridin-3-yl)ethyl)thiophene-2-sulfonamide; N-[2-(4-Methylbenzenesulfonyl)-2-(pyridin-3-yl)ethyl]thiophene-2-sulfonamide; 3-[2-[(Thiophen-2-ylsulfonyl)amino]-1-(4-tolylsulfonyl)ethyl]pyridine
EINECS	Contact for details

Quality Control

Our n-{2-[(4-Methylphenyl)Sulfonyl]-2-(Pyridin-3-Yl)Ethyl}Thiophene-2-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.