Description

8-Nitroimidazo[1,2-A]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting infectious diseases or oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Used in the process development and scale-up manufacturing of new chemical entities (NCEs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical pipelines.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API production.

Basic Information

Product Name	8-Nitroimidazo[1,2-A]Pyridine-2-Carboxylic Acid
CAS No.	904805-44-3
Molecular Formula	C8H5N3O4
Molecular Weight	207.14 g/mol
Synonyms	8-Nitroimidazo[1,2-a]pyridine-2-carboxylic acid; 2-Imidazo[1,2-a]pyridinecarboxylic acid, 8-nitro-; 8-Nitro-2-imidazo[1,2-a]pyridinecarboxylic acid; 904805-44-3; 8-Nitroimidazo[1,2-a]pyridine-2-carboxylate; 8-Nitro-2-carboxyimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 8-Nitroimidazo[1,2-A]Pyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.