Description

5-(Bromomethyl)-2-Chloro-3-Iodopyridine is a high-value, multi-halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring bromomethyl, chloro, and iodo substituents, makes it an exceptionally reactive intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, nucleophilic substitutions, and as a precursor for functionalized heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of the iodine and bromine atoms, enabling efficient carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized to synthesize complex pyridine-based ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a starting material for creating tagged molecules and probes used in biochemical and diagnostic research.

Basic Information

Product Name	5-(Bromomethyl)-2-Chloro-3-Iodopyridine
CAS No.	904745-62-6
Molecular Formula	C6H4BrClIN
Molecular Weight	332.36 g/mol
Synonyms	2-Chloro-3-iodo-5-(bromomethyl)pyridine; 3-Iodo-2-chloro-5-(bromomethyl)pyridine; 5-Bromomethyl-2-chloro-3-iodopyridine; 2-Chloro-5-(bromomethyl)-3-iodopyridine; Pyridine, 5-(bromomethyl)-2-chloro-3-iodo-
EINECS	Contact for details

Quality Control

Every batch of 5-(Bromomethyl)-2-Chloro-3-Iodopyridine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical research and development processes. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and your specific project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.