Description

3-Bromo-2-Chloro-5-(Chloromethyl)Pyridine is a high-value halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its multi-functional structure, featuring bromo, chloro, and chloromethyl substituents, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	3-Bromo-2-Chloro-5-(Chloromethyl)Pyridine
CAS No.	904745-60-4
Molecular Formula	C6H4BrCl2N
Molecular Weight	240.91 g/mol
Synonyms	5-(Chloromethyl)-3-bromo-2-chloropyridine; 2-Chloro-3-bromo-5-(chloromethyl)pyridine; 3-Bromo-2-chloro-5-chloromethylpyridine; Pyridine, 3-bromo-2-chloro-5-(chloromethyl)-; 904745-60-4; 3-Br-2-Cl-5-CH2Cl-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloro-5-(Chloromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom purity grades or analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.