Description

2-(3-Chloro-4-Fluorophenyl)Pyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the chloro-fluorophenyl moiety contributes to biological activity and environmental stability.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport materials.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental unit for custom synthesis projects requiring specific halogenated biphenyl-like structures.

Basic Information

Product Name	2-(3-Chloro-4-Fluorophenyl)Pyridine
CAS No.	904325-79-7
Molecular Formula	C11H7ClFN
Molecular Weight	207.63 g/mol
Synonyms	3-Chloro-4-fluoro-2-pyridinylbenzene; 2-(3-Chloro-4-fluorophenyl)pyridine; (3-Chloro-4-fluorophenyl)-2-pyridyl; 2-Pyridyl-3-chloro-4-fluorobenzene; 904325-79-7; 3'-Chloro-4'-fluoro-2-pyridinylbenzene; 2-(3-Chloro-4-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(3-Chloro-4-Fluorophenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or otherwise opaque, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.