Description

(1R,2R)-trans-1-Hydroxy-1,2,3,4-Tetrahydro-2-Naphthyl Benzoate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for creating complex, optically active molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Serves as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereocenters with high enantiomeric purity.
• Ligand and Catalyst Development: Used in the design and synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A critical reagent for methodological studies in organic chemistry and medicinal chemistry research programs.
• Process Chemistry: Used in route scouting and optimization for the scalable synthesis of complex organic molecules.

Basic Information

Item	Details
Product Name	(1R,2R)-trans-1-Hydroxy-1,2,3,4-Tetrahydro-2-Naphthyl Benzoate
CAS No.	904316-40-1
Molecular Formula	C17H16O3
Molecular Weight	268.31 g/mol
Synonyms	(1R,2R)-1-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl benzoate; (1R,2R)-1,2,3,4-Tetrahydro-1-hydroxy-2-naphthyl benzoate; trans-(1R,2R)-Tetralin-1-ol, 2-benzoate; Benzoic acid (1R,2R)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl ester; (1R,2R)-THN Benzoate; (1R,2R)-trans-Tetralol benzoate
EINECS	Contact for details

Quality Control

Our (1R,2R)-trans-1-Hydroxy-1,2,3,4-Tetrahydro-2-Naphthyl Benzoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound should be handled in a well-ventilated area, and containers must be kept tightly sealed to protect integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.