Description

2-Pyridinecarboxylic Acid, 4-Amino-6-Chloro-5-Cyano- is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its unique molecular structure, featuring amino, chloro, cyano, and carboxylic acid functional groups on a pyridine core, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. Its precise reactivity profile enables the construction of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 4-Amino-6-Chloro-5-Cyano-
CAS No.	904311-41-7
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Amino-6-chloro-5-cyanopicolinic acid; 4-Amino-6-chloro-5-cyano-2-pyridinecarboxylic acid; 6-Chloro-4-amino-5-cyanopicolinic acid; 5-Cyano-4-amino-6-chloropicolinic acid; 2-Carboxy-4-amino-6-chloro-5-cyanopyridine; Picolinic acid, 4-amino-6-chloro-5-cyano-; 904311-41-7; 4-Amino-6-chloro-5-cyanopyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylic Acid, 4-Amino-6-Chloro-5-Cyano- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.