Description

Methyl 3-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate CAS NO 903630-53-5 is a high-purity, functionalized indane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique fused-ring structure with both amino and ester functionalities makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or functional additive in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic and medicinal chemistry.
• Custom Synthesis: A starting point for the contract manufacturing of complex, non-commercial molecules for various industrial applications.

Basic Information

Product Name	Methyl 3-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate
CAS No.	903630-53-5
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	5-Carbomethoxy-3-aminoindane; Methyl 3-aminoindane-5-carboxylate; 3-Amino-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester; 3-Aminoindane-5-carboxylic acid methyl ester; 5-(Methoxycarbonyl)-1-indanamine; 1H-Indene-5-carboxylic acid, 3-amino-2,3-dihydro-, methyl ester; 903630-53-5; 3-Amino-1-indanecarboxylic acid methyl ester (ambiguous, verify structure).
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.