Description

4-(tert-Butoxycarbonylamino-Methyl)-Nicotinic Acid is a high-purity, protected nicotinic acid derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules, offering a versatile handle for further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs.
• Peptide Mimetics & Conjugation: Used to introduce nicotinic acid scaffolds and protected amine functionalities into peptide-like structures.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Facilitates the attachment of bioactive molecules to carriers, probes, or surfaces via its carboxylic acid and protected amine groups.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	4-(tert-Butoxycarbonylamino-Methyl)-Nicotinic Acid
CAS No.	903094-65-5
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	4-[(tert-Butoxycarbonylamino)methyl]nicotinic acid; 4-[(Boc-amino)methyl]nicotinic acid; 4-(Boc-aminomethyl)nicotinic acid; 4-[(tert-Butoxycarbonylamino)methyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-; Boc-NH-CH2-4-Pyridine-COOH; N-Boc-4-(aminomethyl)nicotinic acid; 4-(N-Boc-aminomethyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our production of 4-(tert-Butoxycarbonylamino-Methyl)-Nicotinic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.