Description

2-Ethoxy-5-Iodo-Pyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for the construction of complex molecules, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring both an ethoxy and an iodine substituent, makes it an ideal intermediate for cross-coupling reactions and further functionalization. Industries engaged in the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands will find this high-purity intermediate essential for their R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific halogenated heterocyclic cores.
• Material Science: Serves as a precursor in the creation of organic electronic materials, including components for OLEDs and liquid crystal displays (LCDs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form complex biaryl systems.
• Ligand Synthesis: Utilized in the preparation of specialized nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Research & Development: A valuable tool for medicinal and synthetic chemists exploring new chemical spaces and reaction pathways.

Basic Information

Product Name	2-Ethoxy-5-Iodo-Pyridine
CAS No.	902837-52-9
Molecular Formula	C7H8INO
Molecular Weight	249.05 g/mol
Synonyms	5-Iodo-2-ethoxypyridine; 2-Ethoxy-5-iodopyridine; 5-Iodo-2-ethoxy-pyridine; Pyridine, 2-ethoxy-5-iodo-; 2-Ethoxypyridine, 5-iodo-; 5-Iodo-2-(ethyloxy)pyridine; 2-Ethoxy-5-iodo-pyridin; 5-Iodo-2-ethoxy-pyridin
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-5-Iodo-Pyridine is produced and tested under a stringent quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.