Description

2-(Boc-Amino)-5-Cyanopyridine is a high-purity, protected amino-pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized pyridine core.
• Peptide Mimetics & Conjugation: The Boc-protected amino group allows for controlled deprotection and subsequent coupling, useful in creating peptide-like structures or bioconjugates.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in homogeneous catalysis and material science applications.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(Boc-Amino)-5-Cyanopyridine
CAS No.	902837-44-9
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	5-Cyano-2-[(tert-butoxycarbonyl)amino]pyridine; 2-[(tert-Butoxycarbonyl)amino]-5-cyanopyridine; tert-Butyl (5-cyano-2-pyridinyl)carbamate; 2-(Boc-amino)-5-cyanopyridine; Boc-5-Cyano-2-aminopyridine; N-Boc-2-Amino-5-cyanopyridine; 2-Amino-5-cyanopyridine N-Boc derivative; (5-Cyanopyridin-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-5-Cyanopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.