Description

n-Cyclopropyl-2-(1-Piperazinyl)Nicotinamide Hydrochloride CAS NO 902836-65-1 is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial labs.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a ligand or probe in biochemical assays to study specific receptor interactions and signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production.

Basic Information

Product Name	n-Cyclopropyl-2-(1-Piperazinyl)Nicotinamide Hydrochloride
CAS No.	902836-65-1
Molecular Formula	C13H19N5O • HCl
Molecular Weight	297.78 g/mol
Synonyms	2-(1-Piperazinyl)-N-cyclopropyl-3-pyridinecarboxamide hydrochloride; N-Cyclopropyl-2-piperazin-1-ylpyridine-3-carboxamide hydrochloride; 2-Piperazin-1-yl-N-cyclopropylnicotinamide hydrochloride; CPNP HCl; n-Cyclopropyl-2-(piperazin-1-yl)nicotinamide HCl; 902836-65-1; UNII-9F8F0J8V4C
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-2-(1-Piperazinyl)Nicotinamide Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and pharmaceutical development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development toward cGMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.