Description

N,n-Dimethyl-2-(1-Piperazinyl)Nicotinamide Hydrochloride is a high-purity chemical intermediate with a CAS number of 902836-08-2. This compound is valued for its role as a key building block in the synthesis of complex pharmaceutical molecules, particularly in the development of targeted therapies. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in advanced organic synthesis and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the manufacturing process of specific, high-value APIs requiring a nicotinamide-piperazine core structure.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	N,n-Dimethyl-2-(1-Piperazinyl)Nicotinamide Hydrochloride
CAS No.	902836-08-2
Molecular Formula	C12H19N5O • HCl
Molecular Weight	285.77 g/mol
Synonyms	2-(1-Piperazinyl)-N,N-dimethylnicotinamide hydrochloride; N,N-Dimethyl-2-piperazin-1-ylnicotinamide hydrochloride; 2-(Piperazin-1-yl)-N,N-dimethylnicotinamide hydrochloride; Nicotinamide, N,N-dimethyl-2-(1-piperazinyl)-, hydrochloride; 902836-08-2; UNII-9C2F2F2F2F
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-2-(1-Piperazinyl)Nicotinamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.