Description

8-Bromo-2-(Chloromethyl)-6-Methylimidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both bromo and chloromethyl reactive handles, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a core structure for creating new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the synthesis of organic semiconductors, ligands for catalysis, and advanced polymers due to its rigid, conjugated imidazopyridine core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	8-Bromo-2-(Chloromethyl)-6-Methylimidazo[1,2-A]Pyridine
CAS No.	901124-75-2
Molecular Formula	C9H8BrClN2
Molecular Weight	259.53 g/mol
Synonyms	8-Bromo-2-(chloromethyl)-6-methylimidazo[1,2-a]pyridine; 2-(Chloromethyl)-8-bromo-6-methylimidazo[1,2-a]pyridine; 901124-75-2; Imidazo[1,2-a]pyridine, 8-bromo-2-(chloromethyl)-6-methyl-; 6-Methyl-8-bromo-2-chloromethylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-2-(Chloromethyl)-6-Methylimidazo[1,2-A]Pyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include critical parameters such as assay (HPLC), related substances, and residual solvents. Our commitment to cGMP and ISO guidelines ensures the material meets the stringent requirements of advanced R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The compound may be moisture-sensitive; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.