Description

(8-Chloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(pyridin-3-yl)methanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on developing central nervous system (CNS) and oncological drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• CNS Drug Development: Employed in the research of potential therapeutics for neurological disorders, leveraging its fused indole and pyridine pharmacophores.
• Oncology Research: Utilized in the design and synthesis of novel small-molecule inhibitors for various kinase targets involved in cancer progression.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(8-Chloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(pyridin-3-yl)methanone
CAS No.	900886-90-0
Molecular Formula	C17H14ClN3O
Molecular Weight	311.77 g/mol
Synonyms	8-Chloro-2-(pyridine-3-carbonyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole; 8-Chloro-2-(3-pyridinylcarbonyl)-1,2,3,4,5,6-hexahydropyrido[4,3-b]indole; 900886-90-0; (8-Chloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(3-pyridinyl)methanone; 3-Pyridinecarboxylic acid, 8-chloro-1,2,3,4,5,6-hexahydro-2-pyrido[4,3-b]indol-2-yl ester
EINECS	Contact for details

Quality Control

Our (8-Chloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(pyridin-3-yl)methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.