Description

4-Pyridinecarbonitrile, 3-Chloro-5-(4-Nitrophenyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring pyridine, nitrile, chloro, and nitrophenyl moieties, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, receptor modulators, and other biologically active molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Functional Material Development: Building block for organic electronic materials, such as non-linear optical (NLO) materials or molecular sensors, due to its electron-withdrawing groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this specialized scaffold.

Basic Information

Item	Detail
Product Name	4-Pyridinecarbonitrile, 3-Chloro-5-(4-Nitrophenyl)-
CAS No.	900863-79-8
Molecular Formula	C12H6ClN3O2
Molecular Weight	259.65 g/mol
Synonyms	3-Chloro-5-(4-nitrophenyl)isonicotinonitrile; 3-Chloro-5-(4-nitrophenyl)-4-pyridinecarbonitrile; 4-Cyano-3-chloro-5-(4-nitrophenyl)pyridine; Isonicotinonitrile, 3-chloro-5-(4-nitrophenyl)-; 3-Chloro-5-(p-nitrophenyl)isonicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarbonitrile, 3-Chloro-5-(4-Nitrophenyl)- is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research and scale-up processes. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.