Description

Ethyl 5-(Trifluoromethyl)Thiazole-4-Carboxylate is a high-value trifluoromethylated heterocyclic building block essential for modern synthetic chemistry. This compound is prized for its ability to impart desirable metabolic stability and lipophilicity to target molecules, making it a critical intermediate in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for functionalized thiazole derivatives used in organic electronics, such as OLED materials and conductive polymers.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing enzyme inhibitors, fluorescent probes, and other biochemical tools.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services and scale-up projects in fine chemical production.

Basic Information

Product Name	Ethyl 5-(Trifluoromethyl)Thiazole-4-Carboxylate
CAS No.	900530-66-7
Molecular Formula	C7H6F3NO2S
Molecular Weight	225.19 g/mol
Synonyms	Ethyl 5-(trifluoromethyl)-1,3-thiazole-4-carboxylate; 4-Thiazolecarboxylic acid, 5-(trifluoromethyl)-, ethyl ester; 5-(Trifluoromethyl)thiazole-4-carboxylic acid ethyl ester; Ethyl 5-(trifluoromethyl)-4-thiazolecarboxylate; 900530-66-7; 5-Trifluoromethyl-thiazole-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(Trifluoromethyl)Thiazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.