Description

3-Pyridinecarboxylic Acid, 2-(1-Piperazinyl)-, Ethyl Ester, Hydrochloride (1:2) is a high-purity, specialized organic salt with significant potential as a key synthetic intermediate. This compound is valued for its unique molecular architecture, which combines pyridine and piperazine pharmacophores, making it a versatile building block for advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Employed in organic chemistry research for constructing complex nitrogen-containing heterocycles and fine chemicals.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalytic processes and metal complexation studies.
• Academic and R&D Laboratories: Utilized in universities and corporate R&D for methodological studies and exploring new chemical entities.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2-(1-Piperazinyl)-, Ethyl Ester, Hydrochloride (1:2)
CAS No.	900183-96-2
Molecular Formula	C12H17N3O2 • 2HCl
Molecular Weight	316.21 g/mol (as free base: 235.29 g/mol)
Synonyms	2-(1-Piperazinyl)nicotinic acid ethyl ester dihydrochloride; Ethyl 2-piperazin-1-ylnicotinate dihydrochloride; 2-Piperazin-1-yl-nicotinic acid ethyl ester hydrochloride (1:2); 2-(Piperazin-1-yl)nicotinic acid ethyl ester dihydrochloride; Nicotinic acid, 2-(1-piperazinyl)-, ethyl ester, dihydrochloride
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboxylic Acid, 2-(1-Piperazinyl)-, Ethyl Ester, Hydrochloride (1:2) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.