Description

5-Oxo-5-[4-(1-Pyrrolidinylcarbonyl)Anilino]-Pentanoic Acid is a high-purity, non-natural amino acid derivative and a key synthetic intermediate in advanced pharmaceutical research. Its molecular structure, featuring a pyrrolidine amide and a carboxylic acid terminus, makes it a versatile building block for constructing complex bioactive molecules. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors, particularly for the synthesis of targeted therapeutics and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for protease inhibitors and other enzyme-targeted drugs.
• Peptidomimetic Research: Used to create and modify peptide analogs to enhance metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds and probes to study enzyme function and cellular pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex drug candidates.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and organic synthesis methodologies.

Basic Information

Product Name	5-Oxo-5-[4-(1-Pyrrolidinylcarbonyl)Anilino]-Pentanoic Acid
CAS No.	900080-57-1
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.35 g/mol
Synonyms	5-Oxo-5-[(4-(pyrrolidine-1-carbonyl)phenyl)amino]pentanoic acid; 4-[(4-Pyrrolidin-1-ylcarbonyl)anilino]-4-oxobutanoic acid; 5-[4-(1-Pyrrolidinylcarbonyl)anilino]-5-oxopentanoic acid; 4-[[4-(Pyrrolidine-1-carbonyl)phenyl]amino]-4-oxobutanoic acid; 5-Oxo-5-(4-(pyrrolidine-1-carbonyl)phenylamino)pentanoic acid; N-[4-(1-Pyrrolidinylcarbonyl)phenyl]glutaramidic acid; Glutaramide acid derivative (CAS 900080-57-1)
EINECS	Contact for details

Quality Control

Our 5-Oxo-5-[4-(1-Pyrrolidinylcarbonyl)Anilino]-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.