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3-Bromo-8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine CAS NO 900019-65-0


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CAS No.:900019-65-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Bromo-8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates bromine, chlorine, and a trifluoromethyl group on an imidazopyridine scaffold, enabling precise structural modifications for property optimization. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
  • Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
  • Material Science: Serves as a building block for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and electronic chemicals.
  • Chemical Biology: Employed as a molecular probe or tag due to its distinct halogenated pattern, useful in bio-conjugation and labeling studies.
  • Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name 3-Bromo-8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine
CAS No. 900019-65-0
Molecular Formula C8H3BrClF3N2
Molecular Weight 299.47 g/mol
Synonyms 3-Bromo-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 3-bromo-8-chloro-6-(trifluoromethyl)-; 900019-65-0; 3-Br-8-Cl-6-CF3-Imidazo[1,2-a]pyridine; 6-(Trifluoromethyl)-3-bromo-8-chloroimidazo[1,2-a]pyridine
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Quality Control

Our 3-Bromo-8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP (Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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