Description

1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-2-[(Z)-Ethoxymethylidene]-1,3-Butanedione is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine and diketone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile building block for introducing specific functional groups. It is primarily utilized by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Serves as a crucial building block for developing advanced pesticides, herbicides, and fungicides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities, reaction pathways, and structure-activity relationships (SAR).
• Ligand and Catalyst Development: The diketone functionality makes it a potential candidate for creating chelating ligands used in catalysis and material science.
• Specialty Fine Chemicals: Employed in the production of complex, high-value fine chemicals for various industrial and research applications.

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-2-[(Z)-Ethoxymethylidene]-1,3-Butanedione
CAS No.	900014-69-9
Molecular Formula	C13H9ClF3NO3
Molecular Weight	319.66 g/mol
Synonyms	2-[(Z)-Ethoxymethylene]-1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butane-1,3-dione; (Z)-1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(ethoxymethylene)butane-1,3-dione; 1,3-Butanedione, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-[(Z)-ethoxymethylidene]-; CAS 900014-69-9; 3-Chloro-5-(trifluoromethyl)pyridine diketone derivative; Z-Isomer of ethoxymethylidene substituted pyridinyl butanedione.
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-2-[(Z)-Ethoxymethylidene]-1,3-Butanedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing specific batch results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Isomeric Purity (Z-Isomer)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.