Description

Diethyl 3-Hydroxycyclobutane-1,1-Dicarboxylate is a high-purity, versatile cyclobutane derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique strained-ring structure and bifunctional reactivity, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its cyclobutane core for enhanced biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial labs for constructing complex natural products and exploring new chemical spaces via ring-opening and functionalization reactions.
• Ligand and Catalyst Development: Utilized for creating novel chiral ligands and organocatalysts due to its potential for introducing stereogenic centers.

Basic Information

Product Name	Diethyl 3-Hydroxycyclobutane-1,1-Dicarboxylate
CAS No.	99974-66-0
Molecular Formula	C10H16O5
Molecular Weight	216.23 g/mol
Synonyms	3-Hydroxycyclobutane-1,1-dicarboxylic acid diethyl ester; Diethyl 3-hydroxycyclobutane-1,1-dicarboxylate; 1,1-Bis(ethoxycarbonyl)-3-hydroxycyclobutane; 3-Hydroxy-1,1-cyclobutanedicarboxylic Acid Diethyl Ester; Ethyl 3-hydroxycyclobutane-1,1-dicarboxylate; Diethyl 3-hydroxy-1,1-cyclobutanedicarboxylate
EINECS	Contact for details

Quality Control

Our Diethyl 3-Hydroxycyclobutane-1,1-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.