Description

Bicyclo[2.2.1]Hepta-2,5-Diene-2-Carboxylic Acid, Methyl Ester, (1R,4S)- (9Ci) is a high-purity, chiral bicyclic diene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its rigid, strained structure and defined stereochemistry make it an invaluable building block for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates and bioactive molecules.
• Ligand & Catalyst Precursor: Used in the development of novel organometallic catalysts and chiral ligands for asymmetric catalysis.
• Material Science Research: Serves as a monomer or cross-linking agent in the synthesis of polymers with unique thermal or mechanical properties.
• Agrochemical Synthesis: Employed in the research and development of advanced, stereochemically-defined agrochemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.
• Fine Chemical Production: Used in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hepta-2,5-Diene-2-Carboxylic Acid, Methyl Ester, (1R,4S)- (9Ci)
CAS No.	99946-16-4
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(1R,4S)-Bicyclo[2.2.1]hepta-2,5-diene-2-carboxylic acid methyl ester; (1R,4S)-2,5-Norbornadiene-2-carboxylic acid methyl ester; Methyl (1R,4S)-2,5-norbornadiene-2-carboxylate; (1R,4S)-exo-2,5-Norbornadiene-2-carboxylic acid methyl ester; (1R,4S)-Methyl bicyclo[2.2.1]hepta-2,5-diene-2-carboxylate; (1R,4S)-NBD-COOMe; Chiral norbornadiene ester
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hepta-2,5-Diene-2-Carboxylic Acid, Methyl Ester, (1R,4S)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting compliance with research and cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.