Description

(1R*,2S*,5R*)-(7-Oxo-6-Oxa-Bicyclo[3.2.1]Oct-2-Yl)-Carbamic Acid Benzyl Ester is a high-purity, stereochemically defined bicyclic lactone derivative with a protected carbamate functional group. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the synthesis of complex bioactive molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemistry and high chemical purity for lead optimization and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and central nervous system (CNS) drug candidates.
• Agrochemical Research: Used as a precursor in the synthesis of advanced herbicides, fungicides, and insecticides with specific stereochemical requirements for enhanced efficacy.
• Asymmetric Synthesis: Serves as a versatile scaffold in catalytic asymmetric reactions and chiral pool synthesis for constructing complex molecular architectures.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and fragment-based drug design due to its rigid bicyclic framework and modifiable functional groups.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for target molecules in a GMP environment.
• Academic & Institutional Research: A valuable reagent for methodological development in organic synthesis and chemical biology studies.

Basic Information

Item	Details
Product Name	(1R*,2S*,5R*)-(7-Oxo-6-Oxa-Bicyclo[3.2.1]Oct-2-Yl)-Carbamic Acid Benzyl Ester
CAS No.	99929-67-6
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	Benzyl (1R*,2S*,5R*)-7-oxo-6-oxabicyclo[3.2.1]oct-2-ylcarbamate; 6-Oxabicyclo[3.2.1]octane-7-one, 2-[[(phenylmethoxy)carbonyl]amino]-, (1R*,2S*,5R*)-rel-; (rel-(1R,2S,5R)-2-(((Benzyloxy)carbonyl)amino)-7-oxo-6-oxabicyclo[3.2.1]octan-1-yl)carbamate; Bicyclic Lactone Carbamate; 99929-67-6; Benzyl N-[(1R*,2S*,5R*)-7-oxo-6-oxabicyclo[3.2.1]oct-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our (1R*,2S*,5R*)-(7-Oxo-6-Oxa-Bicyclo[3.2.1]Oct-2-Yl)-Carbamic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent industry standards for advanced intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.