Description

4-Pyridinecarbonyl Chloride, 2-Methyl- (9Ci) is a versatile and reactive heterocyclic building block used in advanced organic synthesis. Its core value lies in its ability to introduce the 2-methylpyridine-4-carbonyl moiety, a key structural feature in the development of pharmaceuticals and agrochemicals. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel active compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the pyridine core is a common bioactive scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or binding properties.
• Chemical Biology Probes: Utilized to create labeled compounds or affinity probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Pyridinecarbonyl Chloride, 2-Methyl- (9Ci)
CAS No.	99911-04-3
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	2-Methylisonicotinoyl chloride; 2-Methylpyridine-4-carbonyl chloride; 4-Carboxy-2-methylpyridine chloride; 2-Picoline-4-carbonyl chloride; 2-Methyl-4-pyridinecarbonyl chloride; Isonicotinic acid, 2-methyl-, chloride; 2-Methylisonicotinic acid chloride
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarbonyl Chloride, 2-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.