Description

17-Hydroxy-3-Aza-A-Homo-4-Androsten-4-One (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is a sophisticated synthetic steroid derivative with a nitrogen mustard moiety, representing a key intermediate in advanced pharmaceutical research. This compound is engineered for targeted therapeutic applications, offering researchers a precise tool for developing novel agents. It is primarily utilized in the development of specialized pharmaceutical compounds, particularly in oncology and endocrinology research, where its unique structure enables specific biological interactions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroid-based therapeutic agents.
• Oncological Research: Used in the development and study of targeted chemotherapeutic prodrugs due to its nitrogen mustard (bis(2-chloroethyl)amino) functional group.
• Endocrine System Studies: Applied in research focused on hormone receptor modulation and the development of selective enzyme inhibitors.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties.
• Biochemical Probe: Utilized as a tool compound to investigate specific biochemical pathways and cellular mechanisms.
• Preclinical Development: Employed in the early-stage development of new chemical entities (NCEs) for various disease targets.

Basic Information

Item	Detail
Product Name	17-Hydroxy-3-Aza-A-Homo-4-Androsten-4-One (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate
CAS No.	99876-94-5
Molecular Formula	C30H42Cl2N2O3
Molecular Weight	549.58 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenyl 17-Hydroxy-3-aza-A-homo-4-androsten-4-one butyrate; 3-Aza-A-homoandrost-4-en-4-one, 17-hydroxy-, 4-[bis(2-chloroethyl)amino]phenyl butanoate; Nitrogen mustard steroid conjugate; Steroidal nitrogen mustard prodrug intermediate; Aza-homo-androstenone phenylbutyrate mustard
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-3-Aza-A-Homo-4-Androsten-4-One (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. This product is strictly light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture must be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.