Description

Z-L-Aspartic Acid β-Allyl Ester is a protected derivative of the amino acid L-aspartic acid, featuring a Z (benzyloxycarbonyl) group for N-terminal protection and a β-allyl ester moiety. This compound is a crucial chiral building block in organic synthesis, enabling the controlled introduction of aspartic acid into peptide chains and other complex molecules while allowing for selective deprotection strategies. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and advanced materials sectors for the synthesis of peptides, peptidomimetics, and specialized fine chemicals.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS), particularly for incorporating aspartic acid residues.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs), especially those with peptide-based structures.
• Bioconjugation: The allyl ester protecting group can be utilized in orthogonal deprotection strategies for the site-specific modification of peptides and proteins.
• Chemical Biology Probes: Acts as a building block for creating labeled or modified amino acid analogs used in studying biological processes.
• Catalyst and Ligand Development: May be employed in the synthesis of chiral catalysts or ligands for asymmetric synthesis.
• Material Science: Potential use in creating functionalized polymers or dendrimers with amino acid components.

Basic Information

Item	Detail
Product Name	Z-L-Aspartic Acid β-Allyl Ester
CAS No.	99793-10-9
Molecular Formula	C15H17NO6
Molecular Weight	307.30 g/mol
Synonyms	N-Carbobenzoxy-L-aspartic acid β-allyl ester; Z-Asp-OAll; Nα-Z-L-Aspartic acid 4-allyl ester; (S)-2-((((Benzyloxy)carbonyl)amino)butanedioic acid 4-allyl ester; Z-L-Asp-OAll; N-Cbz-L-aspartic acid β-allyl ester; Benzyl N-[(1S)-3-(allyloxy)-1-carboxy-3-oxopropyl]carbamate; Allyl (S)-2-((((benzyloxy)carbonyl)amino)succinate
EINECS	Contact for details

Quality Control

Our Z-L-Aspartic Acid β-Allyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and reliable batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.