Description

1-Naphthyl Triflate is a high-purity organic trifluoromethanesulfonate ester, a key reagent in advanced organic synthesis. Its primary value lies in its exceptional reactivity as a robust leaving group, facilitating critical carbon-carbon and carbon-heteroatom bond-forming reactions under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to synthesize complex molecules and novel polymeric materials.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing complex drug candidates, particularly in cross-coupling reactions like Suzuki, Negishi, and Stille couplings.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, enabling the introduction of the naphthyl moiety into active ingredients.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Catalyst & Ligand Preparation: Employed in the synthesis of organometallic catalysts and sophisticated ligands for asymmetric catalysis.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D labs for methodology development and the synthesis of natural products.
• Fine Chemical Production: Used in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-Naphthyl Triflate
CAS No.	99747-74-7
Molecular Formula	C11H7F3O3S
Molecular Weight	276.23 g/mol
Synonyms	1-Naphthyl Trifluoromethanesulfonate; α-Naphthyl Triflate; Naphthalen-1-yl Trifluoromethanesulfonate; 1-Naphthalenyl Triflate; 1-Naphthyl Trifluoromethanesulphonate; Trifluoromethanesulfonic Acid 1-Naphthyl Ester; 1-Naphthyl Trifluoromethylsulfonate
EINECS	Contact for details

Quality Control

Our 1-Naphthyl Triflate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.